Welcome to the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Environmental Exposures and Health.
This HPRU brings together our expertise in air quality measurement and modelling, exposure assessment, conducting large-scale epidemiological studies, biomarkers and disease mechanisms and chemical toxicology of fibres and particles to produce the scientific evidence needed to support the effective protection of the population from these environmental hazards.
This HPRU is led by Imperial College London in partnership with Public Health England, King’s College London and the MRC Toxicology Unit, Cambridge.
We have strong links with the Chemical and Radiation Threats and Hazards HPRU and the MRC Centre for Environment and Health and to ensure we operate as a highly collaborative matrix, analogous to PHE’s multi-functional, single-agency model, we have created a Joint Steering Committee, Training Programme Committee, Public and Community Involvement, Engagement and Participation Committee and Public and Community Oversight Group.
The mission of this HPRU is to undertake the highest quality research on the health effects associated with exposure to a range of environmental pollutants, including those in the ambient and indoor settings. Our aims are to improve the understanding of the distribution, determinants and pathways linking these exposures to health effects, to provide scientific evidence that will impact directly on public health practice and policy, and to train the next generation of research leaders in environment and health.
In addition, we will look at emerging exposure issues including e-cigarettes, microplastics, illicit and herbal drug use and brake and tyre wear toxicology.
1. What are the exposures to toxicants from all environmental sources and consumer products in different populations?
2. Can models be developed to predict exposure?
3. What is the public perception of risk from these toxicants and how are potential risks best communicated?
1. What biomarkers emerge following acute exposure to different air pollutants and do they discriminate between different sources?
2. Are non-exhaust PM emissions (brake, tyre and road wear) of toxicological relevance and what are the relative toxicities of exhaust PM and NO2?
3. What are the relative toxicities of e-cigarette components?
1. What are the impacts of air pollution on birth outcomes, cognitive development, mental health and dementia in later life ?
2. What are the impacts of traffic related air pollution on school children’s neurodevelopment and overall health and to what extent does the ULEZ mitigate against any adverse effects ?
3. What, if any, is the impact of air pollution on the London Underground?
1. Do microplastics have detrimental human health effects?
2. What are the baseline exposures for key air pollutants prior to fracking being commenced?
3. What are the health impacts of living near biomass electricity generating installations or being exposed to waste fire emissions?
This HPRU brings together the expertise in air quality measurement and modelling, exposure assessment, conducting large-scale epidemiological studies, biomarkers and disease mechanisms and chemical toxicology of fibres and particles from four leading UK research partners to produce the scientific evidence needed to support the effective protection of the population from these environmental hazards.